📊 TCRbase Repertoire & Single-Cell Response

Paired αβ & γδ

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Expressed Rearranged TCRs across Viral Infections, Cancer TILs & Single-Cell Phenotypes • Native Rust PaCMAP

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3,200TCR Single Cells

10Immune Responses

9T-Cell Phenotypes

Pairedαβ Clonotypes

Color Dimension:

🔬 TCR Paired Single-Cell Inspector

Click on any point on the TCR response manifold to inspect its paired αβ chains, cell barcode, functional T-cell phenotype, and clonal expansion dynamics.

CURATED SINGLE-CELL RESPONSE PRESETS:

🟢 NY-ESO-1 1G4 (Melanoma TIL • Tex)

🔵 Flu A M1 (GILGFVFTL • Memory)

🟣 CMV pp65 (NLVPMVATV • Tem)

🟠 SARS-CoV-2 (Spike 269 • Activated)

🟡 Murine OT-I (OVA SIINFEKL • CTL)

🟤 Human MAIT (TRAV1-2 Invariant)

🔴 Bovine WC1+ (Somatic γδ TCR)

Barcode: - Response: - Phenotype: - Expansion: -

Antigen Epitope: -

MHC Restriction: -

Species / Organism: -

Primary Chain (TRB / TRD) ●

V-Gene: -

J-Gene: -

CDR3 Loop: -

Len: - • Charge: - • Hyd: -

Paired Chain (TRA / TRG) ●

V-Gene: -

J-Gene: -

CDR3 Loop: -

Len: - • Charge: - • Hyd: -

ℹ️ Single-cell clonotypes are placed via PaCMAP from hypervariable CDR3 sequence chemistry, V/J usage, and functional expansion profiles.