VBASE3 Species Status & Coverage Monitor

Immunogenomic Coverage & Alignment Release Policy

To guarantee synthesis-grade fidelity and eliminate spurious alignments from draft fragment loci, VBASE3 adheres to an objective Coverage Gating Policy. Dedicated search portals and SIMD alignment workbenches are provided for any vertebrate species that achieves ≥ 80% verified coverage (confirmed functional Class I germlines, physiological AIRR repertoire validation, and strict J-segment boundary compliance). Species currently under 80% remain transparently cataloged as assemblies mature.

Master Release Taxa (55 Assemblies)

2,857

Class I Master Export (Stratum 3)

Dedicated Search Portals (≥80%)

8,329

Total Curated Alleles (Stratum 1 Archive)

⚖️ Objective Coverage Gating Criteria

≥ 80% Coverage (Search Portal Live): High-confidence chromosome-level or deep Sanger locus assembly, verified functional Class I V-genes confirmed with rearranged repertoire reads, multi-locus heavy and light chain representation, and exact IMGT C-terminal J-segment boundaries (TVSS/TVSA for Heavy; VEIK/LEIK for Kappa; TVL for Lambda).
< 80% Coverage (Assembly & Curation in Progress): Fragmentary scaffolds, unverified pseudogene arrays, or pending AIRR-seq experimental verification. Kept active in internal research partitions and monitored dynamically until coverage milestones are met.

Showing 43 detailed workbench species (from 53 master release taxa)

Vertebrate Species	Clade	Estimated Coverage	Class I V-Genes	Pseudogenes	J & D Segments	Repertoire Evidence	Synthesis Boundaries	Search Portal
House Mouse Mus musculus	Rodents	98%	2,763	345	✅ Verified	15M+ AIRR reads, Dildrop families	TVSS (Heavy) / VEIK (Kappa)	⚡ Launch Search
Human Homo sapiens	Primates	98%	850	634	✅ Verified	30M+ AIRR reads (OAS/iReceptor)	TVSS (Heavy) / VEIK (Kappa) / TVL (Lambda)	⚡ Launch Search
Alpaca Vicugna pacos	Camelids	96%	312	55	✅ Verified	Autonomous VHH Nanobodies	TVSS (FR2 Hallmarks)	⚡ Launch Search
European Rabbit Oryctolagus cuniculus	Lagomorphs	95%	345	858	✅ Verified	Rab_IGHV1 + GALT gene conversion	TVSS / VEIK (Cys21-Cys79 bridge)	⚡ Launch Search
Chicken Gallus gallus	Birds	95%	2	240	✅ Verified	OmniChicken & DT40 Gene Conversion	TVSS / TVL (Single V-region)	⚡ Launch Search
Rhesus Macaque Macaca mulatta	Primates	94%	476	341	✅ Verified	5M+ AIRR reads (NHP models)	TVSS / VEIK / TVL	⚡ Launch Search
Norway Rat Rattus norvegicus	Rodents	92%	537	121	✅ Verified	2M+ AIRR reads	TVSS / VEIK	⚡ Launch Search
Domestic Dog Canis lupus familiaris	Carnivores	92%	142	140	✅ Verified	Veterinary mAbs (Lokivetmab)	TVSS / TVL (~90% Lambda)	⚡ Launch Search
African Clawed Frog Xenopus laevis	Amphibians	90%	300	712	✅ Verified	Allotetraploid L/S subgenomes	TVSS / TVL (Ig-Rho / Ig-Sigma)	⚡ Launch Search
Cattle Bos taurus	Artiodactyls	88%	174	92,218	✅ Verified	Ultralong CDR-H3 (up to 68 aa)	TVSS / TVL (~95% Lambda)	⚡ Launch Search
Arabian Camel Camelus dromedarius	Camelids	88%	55	71	⚠️ Draft	VHH single-domain libraries	TVSS	⚡ Launch Search
Wild Boar / Swine Sus scrofa	Artiodactyls	86%	207	360	✅ Verified	Porcine xenotransplantation models	TVSS / VEIK	⚡ Launch Search
Horse Equus caballus	Perissodactyls	85%	192	274,546	✅ Verified	Equine therapeutic repertoires	TVSS / TVL (~90% Lambda)	⚡ Launch Search
Domestic Cat Felis catus	Carnivores	85%	85	0	⚠️ Draft	Veterinary mAbs (Frunevetmab)	TVSS / VEIK / TVL	⚡ Launch Search
Domestic Sheep Ovis aries	Artiodactyls	84%	145	32,672	✅ Verified	Ileal Peyer patch diversification	TVSS / TVL	⚡ Launch Search
Crab-eating Macaque Macaca fascicularis	Primates	82%	249	4	⚠️ Draft	Preclinical toxicology models	TVSS / VEIK	⚡ Launch Search
Zebrafish Danio rerio	Teleost Fish	78%	204	72	⚠️ Draft	IgZ/IgT mucosal teleost model	TVSS / TVL (Pending J-refinement)	⏳ Maturing (<80%)
Rainbow Trout Oncorhynchus mykiss	Teleost Fish	68%	199	14	⚠️ Draft	Teleost tetrameric IgM	In Progress	⏳ Maturing (<80%)
Ferret Mustela putorius furo	Carnivores	62%	83	3	⚠️ Draft	Respiratory influenza models	In Progress	⏳ Maturing (<80%)
Guinea Pig Cavia porcellus	Rodents	58%	154	0	⚠️ Draft	Contact hypersensitivity model	In Progress	⏳ Maturing (<80%)
Mallard Duck Anas platyrhynchos	Birds	55%	103	95,464	⚠️ Draft	Avian influenza reservoir	In Progress	⏳ Maturing (<80%)
Gray Short-tailed Opossum Monodelphis domestica	Marsupials	52%	108	0	⚠️ Draft	Metatherian comparative immunology	In Progress	⏳ Maturing (<80%)
Platypus Ornithorhynchus anatinus	Monotremes	50%	31	0	⚠️ Draft	Prototherian ancestral locus	In Progress	⏳ Maturing (<80%)
Elephant Shark Callorhinchus milii	Chondrichthyes	48%	1	462,315	⚠️ Draft	Cartilaginous fish NAR / IgW	In Progress	⏳ Maturing (<80%)
Small-spotted Catshark Scyliorhinus canicula	Chondrichthyes	45%	31	0	⚠️ Draft	Cartilaginous fish ancestral cluster	In Progress	⏳ Maturing (<80%)
Chimpanzee Chimpanzee	Other Vertebrate	40%	123	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Marmoset Marmoset	Other Vertebrate	40%	101	5	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Shark Shark	Other Vertebrate	40%	80	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Bat Bat	Other Vertebrate	40%	77	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Salmon Salmon	Other Vertebrate	40%	65	3	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Goat Goat	Other Vertebrate	40%	46	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Baboon Baboon	Other Vertebrate	40%	28	2	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Water buffalo Water buffalo	Other Vertebrate	40%	24	76	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Dolphin Dolphin	Other Vertebrate	40%	14	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Buffalo Buffalo	Other Vertebrate	40%	5	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Arabian camel Arabian camel	Other Vertebrate	40%	4	1	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Gorilla Gorilla	Other Vertebrate	40%	4	2	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Hamster Hamster	Other Vertebrate	40%	3	1	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Turtle Turtle	Other Vertebrate	40%	3	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Bottlenose dolphin Bottlenose dolphin	Other Vertebrate	40%	1	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Elephant Elephant	Other Vertebrate	40%	1	0	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Gibbon Gibbon	Other Vertebrate	40%	1	1	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)
Orangutan Orangutan	Other Vertebrate	40%	1	3	⚠️ Draft	Genomic assembly curation	Under Investigation	⏳ Maturing (<80%)